Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 220

Year

2024 1

2023 10

2022 6

2021 19

2020 15

2019 17

2018 14

2017 18

2016 9

2015 21

2014 13

2013 7

2012 8

2011 9

2010 5

2009 4

2008 9

2007 11

2006 1

2005 4

open ︾

Keywords

PD-L1 7

biomaterials 4

Additive manufacturing 2

Biomaterials 2

China 2

DNA 2

PD-1 2

tissue engineering 2

urbanization 2

(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) 1

1512L insulator 1

1D materials 1

2(5H)-furanone 1

3-RPS-manipulator 1

304L austenitic stainless steel 1

316L stainless steel 1

3D photo-fabrication 1

3T3-L1 1

3T3-L1 preadipocyte 1

open ︾

Search scope:

排序： Display mode:

Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Engineering 2017, Volume 3, Issue 1, Pages 16-27 doi: 10.1016/J.ENG.2017.01.003

Abstract: The use of advanced biomaterials and stem cells independently or in conjunction to treat knee OA could

Keywords： Knee osteoarthritis Osteoarthritic pain Mesenchymal stem cells Biomaterials Regenerative engineering

HTML PDF Collect

Mechanically Strong Proteinaceous Fibers: Engineered Fabrication by Microfluidics Review

Jing Sun, Jingsi Chen, Kai Liu, Hongbo Zeng

Engineering 2021, Volume 7, Issue 5, Pages 615-623 doi: 10.1016/j.eng.2021.02.005

Abstract:

Lightweight and mechanically strong natural silk fibers have been extensively investigated over the past decades. Inspired by this research, many artificial spinning techniques (wet spinning, dry spinning, electrospinning, etc.) have been developed to fabricate robust protein fibers. As the traditional spinning methods provide poor control over the as-spun fibers, microfluidics has been integrated with these techniques to allow the fabrication of biological fibers in a well-designed manner, with simplicity and cost efficiency. The mechanical behavior of the developed fibers can be precisely modulated by controlling the type and size of microfluidic channel, flow rate, and shear force. This technique has been successfully used to manufacture a broad range of protein fibers, and can accelerate the production and application of protein fibers in various fields. This review outlines recent progress in the design and fabrication of protein-based fibers based on microfluidics. We first briefly discuss the natural spider silk-spinning process and the microfluidics spinning process. Next, the fabrication and mechanical properties of regenerated protein fibers via microfluidics are discussed, followed by a discussion of recombinant protein fibers. Other sourced protein fibers are also reviewed in detail. Finally, a brief outlook on the development of microfluidic technology for producing protein fibers is presented.

Keywords： Proteinaceous fibers Microfluidics Soft materia l Biomaterials

HTML PDF Collect

Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: Therefore, there is an increasing interest in developing degradable hybrid polymer biomaterials withIn this review, we highlight the design and synthesis of degradable hybrid polymer biomaterials and focus

Keywords： hybrid polymer bone regeneration tissue engineering biomaterials

HTML PDF Collect

Biomimetic Design of Biomaterials

Yao Kangde,Shen Feng

Strategic Study of CAE 2000, Volume 2, Issue 6, Pages 16-20

Abstract:

The research on biomaterials has gotten achievements during the past 30 years.It prompts people to design biomaterials through biomimetic approaches.of artificial extracellular matrixes and the control of apoptosis based on the interaction between biomaterialsIn view of the broadness and flexibility life science, it is recommended to design the biomaterials onof intelligent and environment-friendshiply biomaterials.

Keywords： biomaterials biomimetic artificial ECMs

HTML PDF Collect

Surface modification of biomaterials by photochemical immobilization and photograft polymerization to

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 3, Pages 372-381 doi: 10.1007/s11705-010-0005-z

Abstract: Recent progresses and strategies to improve the hemocompatibility of biomaterials by surface modificationThis surface modification is a promising strategy for biomaterials especially for cardiovascular grafts

Keywords： biomimetic amphiphilic amphiphilic phosphorylcholine endothelial functional biomaterial

HTML PDF Collect

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Strategic Study of CAE 2003, Volume 5, Issue 7, Pages 17-23

Abstract: Nowadays biomaterials matrixes or vectors are developing toward the third generation, i.e. cell or/andIt is sure that biomaterials will play a crucial role in fighting against SARS viruses and the like.

Keywords： Anti-RNA viruses protein DNA polysaccharide biomaterials

HTML PDF Collect

Comments on the special issue on forestry of

John L. INNES

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4, Pages 502-503 doi: 10.15302/J-FASE-2017189

HTML PDF Collect

PD-1/PD-L1 blockade in cervical cancer: current studies and perspectives

Yumeng Wang, Guiling Li

Frontiers of Medicine 2019, Volume 13, Issue 4, Pages 438-450 doi: 10.1007/s11684-018-0674-4

Abstract: Checkpoint blockades targeting the PD-1/PD-L1 axis have achieved effective clinical responses with acceptableIn this review, we summarize recent advances in our understanding of the PD-1/PD-L1 signaling pathway, including the expression patterns of PD-1/PD-L1 and potential PD-1/PD-L1-related therapeutic strategies

Keywords： PD-1 PD-L1 immune checkpoint blockade antibody immunotherapy cervical cancer

HTML PDF Collect

Biocompatibility Pathways in Tissue-Engineering Templates Perspective

David F. Williams

Engineering 2018, Volume 4, Issue 2, Pages 286-290 doi: 10.1016/j.eng.2018.03.007

Abstract: through a systematic combination of molecular and mechanical signals, usually involves the assistance of biomaterials-based

Keywords： Biomaterials Scaffolds Mechanotransduction Inflammation Topography

HTML PDF Collect

In memory of Perry L. McCarty, seminal founder of Environmental Biotechnology

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 10, doi: 10.1007/s11783-023-1730-0

HTML PDF Collect

Shear design of high strength concrete prestressed girders

Emad L. LABIB,Hemant B. DHONDE,Thomas T. C. HSU,Y. L. MO

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4, Pages 373-387 doi: 10.1007/s11709-014-0087-7

Abstract: Normal strength prestressed concrete I-girders are commonly used as the primary superstructure components in highway bridges. However, shear design guidelines for high strength PC girders are not available in the current structural codes. Recently, ten 7.62 m (25 feet) long girders made with high strength concrete were designed, cast, and tested at the University of Houston (UH) to study the ultimate shear strength and the shear concrete contribution ( ) as a function of concrete strength ( ). A simple semi-empirical set of equations was developed based on the test results to predict the ultimate shear strength of prestressed concrete I-girders. The UH-developed set of equations is a function of concrete strength ( ), web area ( ), shear span to effective depth ratio ( / ), and percentage of transverse steel ( ). The proposed UH-Method was found to accurately predict the ultimate shear strength of PC girders with concrete strength up to 117 MPa (17000 psi) ensuring satisfactory ductility. The UH-Method was found to be not as overly conservative as the ACI-318 (2011) code provisions, and also not to overestimate the ultimate shear strength of high strength PC girders as the AASHTO LRFD (2010) code provisions. Moreover, the proposed UH-Method was found fairly accurate and not exceedingly conservative in predicting the concrete contribution to shear for concrete strength up to 117 MPa (17000 psi).

Keywords： shear design high strength concrete prestressed girders full-scale tests

HTML PDF Collect

Deeply missing my career idol and role model ― Professor Perry L. McCarty

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 9, doi: 10.1007/s11783-023-1717-x

HTML PDF Collect

3D Photo-Fabrication for Tissue Engineering and Drug Delivery Review

Rúben F. Pereira, Paulo J. Bártolo

Engineering 2015, Volume 1, Issue 1, Pages 90-112 doi: 10.15302/J-ENG-2015015

Abstract:

The most promising strategies in tissue engineering involve the integration of a triad of biomaterials

Keywords： 3D photo-fabrication biomaterials tissue engineering drug delivery

HTML PDF Collect

Urban watershed management under rapid urbanization

Pengfei DU, Haifeng JIA, Shaw L. YU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 595-595 doi: 10.1007/s11783-012-0452-5

HTML PDF Collect

Recombinant aspartate aminotransferase-catalyzed synthesis of L-4-fluorophenylalanine

CHEN Meijuan, JIA Honghua, CHEN Yongsheng, JIANG Min, WEI Ping

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 2, Pages 220-223 doi: 10.1007/s11705-008-0041-0

Abstract: L-4-Fluorophenylalanine (FPhe) was prepared from 4-fluorophenylpyruvate (FPPA) catalyzed by aspartateconditions: 37°C, pH value range of 5.0–8.0, 5.5 mass ratio of cell to FPPA, 0.6% (w/v) of Tween 80, 7.08 g/LFPPA, and 1.6 of molar ratio of L-Asp to FPPA.

Keywords： L-4-Fluorophenylalanine Asp-AT aspartate aminotransferase 4-fluorophenylpyruvate FPPA